Antifungal compositions

Details Antifungal compositions Antifungal compositions

1999-06-15

2000-10-24

Marx, Irene

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

924499, A61K 3800

Patent

active

061367834

ABSTRACT:
The invention is a pharmaceutical composition for intravenous administration to a patient comprising
a) a pharmaceutically effective amount of a compound having the formula ##STR1## and the pharmaceutically acceptable salts thereof; b) a pharmaceutically acceptable amount of an excipient such as a bulking agent effective to form a lyophilized cake; and
c) a pharmaceutically acceptable amount of acetate buffer effective to provide a pH of between about 4 and 7.

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patent: 5466781 (1995-11-01), Dorin et al.
patent: 5514650 (1996-05-01), Balkovec et al.
patent: 5552521 (1996-09-01), Belyk et al.
patent: 5665760 (1997-09-01), Brown et al.
"The Merck Manual," 16th edition. Berkow, editor. (1992) (Merck & Co., Inc.: Rahway NJ), p. 159-171.
The Merck Manual, 16.sup.th Edition, pp. 159-171 (1992).
Remington's Pharma. Sciences, pp. 1463-1469 and 1478-1484 (1980).
Remington's Pharma. Sciences. p. 238 (1980).
The Determination of Ionization Constants, 3.sup.rd Edition, Chapman & Hall, p. 74 (1984), by Albert, et al.
Remington's Pharma. Sciences, 18.sup.th Edition, Chapter 17, pp. 241-243 (1990).

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