Antifungal 2-azolylmethyl-3-difluorobenzyloxy-2,3-dihydrofluoro-

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514383, 548262, 548330, A61K 31415, A61K 3141, C07D40906

Patent

active

046955798

ABSTRACT:
2-Azolylmethyl-3-difluorobenzyloxy-2,3-dihydro-5- and 6-fluorobenzo[b]thiophen antifungally compounds, especially 2-(1H-imidazolylmethyl-3-(2',6'-difluorobenzyloxy)-2,3-dihydro-5-fluoroben zo[b]thiophene, pharmaceutical compositions containing them and their use in treating fungal infections in animals including humans are disclosed.

REFERENCES:
patent: 4352808 (1982-10-01), Rane et al.
patent: 4431816 (1984-02-01), Rane et al.
patent: 4468404 (1984-08-01), Rane et al.
Loebenberg, D., et al., Abstracts, Interscience Conference in Antimicrobial Agents and Chemotherapy, 1982, Abstract No. 474.
Lennette, E., et al., Manual of Chemical Microbiology, American Society for Microbiology, New York, 1980, pp. 648-649.

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