Antifungal 2-anilinothiazolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

548190, C07D27742, A61K 31425

Patent

active

047882093

ABSTRACT:
Fungal infections of the skin and mucous membranes may be controlled by topical administration of a pharmaceutical composition comprising a N-(3- or 4-alkylphenyl)4,5-dihydro-2-thiazolamine.

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M. Tisler. Synthesis and rearrangement of 1-substituted thiocarbamylethylenimines to N-substituted derivatives of 2-amino-2-thiazoline. Arch. Pharm. 291 457 (1958) CA53:6208i.
H. Najer, et al., 2-Aralkylamino- or arylaminothiazolines possessing vascular activity. Bull. Soc. Chim. France 1960, 960. CA55:1582e.
R. Zhao, et al., Preparation and application of "Jing Song Ling": - a veterinary sedative, analgesic and myorelaxant.
Zhongguo Nongye (Beijing) Kexue (4) 9 (1981). CA96:115796p.

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