Antifungal 1-substituted benzimidazoles

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424270, C07D41700

Patent

active

040175030

ABSTRACT:
New benzimidazoles substituted at the 1-position with carbonyl substituents and at the 2-position with a 4-thiazolyl group are effective fungicides and anthelmintics exhibiting particularly useful hydrophilic and lypophilic effects. The compounds as well as processes for their preparation are described along with antifungal and anthelmintic compositions for their use. The 1-position substituent is a loweralkoxy or phenylloweralkoxy substituted ethoxy or polyethoxy carbonyl group of a chain with up to 4 ethoxy groups connected to the carbonyl. The compounds are generally prepared by contacting a 1-unsubstituted benzimidazole with a loweralkoxy or phenylloweralkoxy substituted ethoxy or polyethoxy chloroformate.

REFERENCES:
patent: 3055907 (1962-09-01), Brown et al.

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