Antifoaming agent for fermentation, L-amino acid-producing mediu

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435812, 252351, 25218227, 252358, 554168, 554227, C12P 1304, C09K 300, C07C 5143

Patent

active

055676065

ABSTRACT:
Disclosed herein are antifoaming agents for fermentation which include, as active ingredient at least one of (a) a reaction product obtained by adding at least one alkylene oxide to a mixture of a fat and/or oil with a trihydric or still higher polyhydric alcohol, or (b) a compound represented by the following general formula (1): ##STR1## wherein n stands for a number of 2-50, R.sup.1, R.sup.2 and R.sup.3 mean individually a hydrogen atom or an acyl group having 2-31 carbon atoms, x denotes an alkylene group having 2-4 carbon atoms, and m1, m2 and m3 are individually a number of 0-200, an L-amino acid-producing medium containing either one of these components, and a production process for L-amino acids making use of this medium. The use of this antifoaming agent permits the quick, sure and durable suppression of bubbling during incubation, and the overall production of the L-amino acid is significantly improved.

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Nippin Oils and Fats Co., Ltd., "Additive for L-quitamic Acid Fermentation", Chemical Abstracts, 94:190310n 1981.

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