Antifibrotic agent

Details Antifibrotic agent Antifibrotic agent

1983-03-25

1985-04-30

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

514532, 514557, A61K 3112, A61K 3119, A61K 31215

Patent

active

045144206

ABSTRACT:
Compounds of the formula ##STR1## wherein A is methylene or carbonyl, n is an integer of 2 to 21, inclusive, and R is hydrogen or lower alkyl, are effective for the prophylaxis or treatment of mammals suffering from fibrosis due to excessive collagen accumulation.

REFERENCES:
patent: 4139545 (1979-02-01), Morimoto
patent: 4248892 (1981-02-01), Kanamaru
patent: 4271083 (1981-06-01), Morimoto et al.
patent: 4358461 (1982-11-01), Maki et al.
J. Uitto et al., Clin. Chem. Acta 30:741-744, 1970.

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