Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Reexamination Certificate
2006-07-11
2006-07-11
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
C514S708000, C514S709000, C514S718000, C514S724000, C549S545000, C560S254000, C568S027000, C568S028000, C568S633000, C568S715000
Reexamination Certificate
active
07074829
ABSTRACT:
This invention relates to new antiestrogens of the general formulain which the substituents have the meanings that are explained in more detail in the description.The new compounds are a) pure antiestrogens or b) antiestrogens with partial estrogenic action (tissue-selective estrogens).Based on these properties, the new compounds are suitable for the production of pharmaceutical agents: in the case of a), for example, for the treatment of breast cancer; in the case of b), for example, for hormone replacement therapy.
REFERENCES:
patent: 4133814 (1979-01-01), Jones et al.
patent: 5994371 (1999-11-01), Black et al.
patent: 6166075 (2000-12-01), Klar et al.
patent: WO 9313123 (1993-08-01), None
Swift R. “Inhibition of melanoma . . . ” CA 126:851112 (1997).
Zajchowski et al. “Identification of selective . . . ” CA 133:144887 (2000).
Guzi et al. “Preparation of substituted . . . ” CA 138:255252 (2003).
J. Lu et al., “Antioestrogenic activity of two 11beta-oestradiol derivatives on MCF-7 breast cancer cells,”Steroids: Structure, Function And Regulation, vol. 60, No. 8, Aug. 1, 1995, pp. 512-518.
Aumann et al., “Steroid-Like Ring Skeletons by Cyclohexadiene Annulation to Enamines with Alkynlcarbene Complexes of Chromium and Tungsten via Pyran-2-ylidene Complexes,”J. Am. Chem. Soc., No. 118, pp. 10853-10861.
Bohlmann Rolf
Fritzemeier Karl-Heinrich
Klar Ulrich
Lessl Monika
Lichtner Rosemarie
Chang Celia
Millen White Zelano & Branigan P.C.
Schering AG
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