Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-09-28
1990-04-10
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
049161407
ABSTRACT:
The disclosure pertains to certain pyrazolopyridincarboxylates which are calcium channel blockers and possess anticonvulsant properties. By virtue of this activity, the compounds are useful in the treatment of epilepsy.
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M. J. Brodie, British Medical Journal, vol. 296, pp. 530-531 (1988).
C. D. Binnie, "Clinical Trials of Flunarizine in Epilepsy", Intl. Symposium on Calcium Antagonists, New York City, Feb. 10-13, 1987.
F. B. Meyer et al., "Anticonvulsant Properties of Dihydropyridine Ca.sup.2+ Antagonists" Intl. Symposium on Calcium Antagonists, New York City, Feb. 10-13, 1987.
A. Scriabine, "Pharmacology of Nimodipine--A Review", Intl. Symposium on Calcium Antagonists, New York City, Feb. 10-13, 1987.
M. R. Tata et al., "Flunarizine in Pharmacoresistant Epilepsies: Preliminary Experiences in 30 Cases", Intl. Symposium on Calcium Antagonists, New York City, Feb. 10-13, 1987.
D. M. Treiman, "Calcium Antagonists in the Treatment of Epilepsy", Intl. Symposium on Calcium Antagonists, New York City, Feb. 10-13, 1987.
R. Trouve et al., "Nitrendipine: An Antidote to the Lethal Toxicity of Cocaine", Intl. Symposium on Calcium Antagonists, New York City, Feb. 10-13, 1987.
Miller Francis P.
Mir Anis
Palfreyman Michael G.
Friedman Stanley J.
Merrell Dow Pharmaceuticals Inc.
Sayles Michael J.
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