Antidote including activated carbon particles

Details Antidote including activated carbon particles Antidote including activated carbon particles

1985-07-29

1988-08-02

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Free carbon containing

A61K 3344

Patent

active

047612843

ABSTRACT:
Disclosed is a pharmaceutical composition having an antidotal activity, which in dosage unit form is capable of adsorbing exogenous or endogenous toxins in the gastrointestinal tract of a patient without disintegration of said pharmaceutical composition and without causing the patient to become constipated. The active ingredient comprises spherical particles of an activated carbon wherein at least 85% in number of said spherical particles of activated carbon are microscopically spherical particles which have smooth and convex-curved surfaces without sharp edges. Specific physical parameters of the carbon particles include, maximum to minimum diameter ratios of 1.0 to 1.3, diameters of 0.05 to 2.0 mm and pore cavity volume of not more than 0.5 cc/g determined in the range of pore-radius of 5000 to 75,000 .ANG.. Dosage unit forms included, capsules, tablets, and aqueous slurries.

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English translation of an Official Action of the Examiner of the Netherlands Patent Office.

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