Antidiabetic method comprising 7-thiaprostaglandin E.sub.1 or it

Details Antidiabetic method comprising 7-thiaprostaglandin E.sub.1 or it Antidiabetic method comprising 7-thiaprostaglandin E.sub.1 or it

1988-05-17

1990-06-26

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514573, 514866, A61K 3119, A61K 31215, A61K 31557

Patent

active

049372653

ABSTRACT:
An antidiabetic composition which comprises a 7-thiaprostaglandin E.sub.1 represented by the formula ##STR1## wherein R.sup.1 is hydrogen atom, a straight-chain or branched-chain alkyl group or one equivalent of cation, R.sup.2 is hydrogen atom or methyl group, R.sup.3 is a straight-chain or branched-chain alkyl group or a cycloalkyl group, n is 0 or 1, and the asterisk represents an asymmtric carbon atom, which can be administered orally to exhibit the desired activity.

REFERENCES:
patent: 4080458 (1978-03-01), Radunz et al.
Chemical Abstracts 99:212335g (1983).
Chemical Abstracts 104:168262b (1986).
Chemical Abstracts, vol. 108, 107025n (1988).
Biochemical and Biophysical Research Communications, vol. 150, pp. 225-230, (1988).

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