Antidiabetic compounds comprising benzofuran and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C549S051000

Reexamination Certificate

active

10580033

ABSTRACT:
The invention relates to compounds of the general formula (I) below:in which R1, R2, R3, R4, R5, R6 and X are as defined in claim1.These compounds can be used in the treatment of pathologies associated with insulin resistance syndrome.

REFERENCES:
patent: 5908859 (1999-06-01), Cullinan et al.
patent: 0 897 918 (1999-02-01), None
patent: WO 99/58519 (1999-11-01), None
patent: WO 99/61435 (1999-12-01), None
Svoboda, Jiri. et al, “Application of magnesium alkoxides to syntheses of benzoheterocyclic compounds,” Collection of Czechoslovak Chemical Communications (1993), vol. 58(3), pp. 592-599.
Darias, V. et al: “Bicyclic Thiophenic Derivatives as Platelet Aggregation Inhibitors” Farmaco, Edizione Scientifica, 41(6), 478-82 Coden: FRPSAX; ISSN: 0430-0920, 1986, XP001194422.
Conde, Santiago et al.: “Analogs of Propranolol. Synthesis of 3-Alkylamino-1-(3-Benzo'b!Thienyloxy)-2-Propanols” Journal of Heterocyclic Chemistry, 17(5), 937-40 Coden: JHTCAD; ISSN: 0022-152X, 1980, XP002286806.
Witiak, Donald T. et al: “9-Chloro-2, 3-Dihydro-5H-1, 4-Dioxepino ′6,5-b! Benzofuran, A Novel Antilipidemic Agent Structurally Related to Clofibrate” Journal of Medicinal Chemistry, 18(10), 992-6 CODEN: JMCMAR; ISSN: 0022-2623, 1975, XP002286807.
Connor, David T. et al: “Novel Benzothiophene-, Benzofuran-, and Naphthalenecarboxamidotetrazoles as Potential Antiallergy Agents” Journal of Medicinal Chemistry, 35(5), 958-65 CODEN: JMCMAR; ISSN: 0022-2623, 1992, XP002286756.
Tondeur, R. et al: “Benzofuran Series XXXV. Amino Derivatives of 3-Benzofuranol” Chimica Therapeutica, 3(5), 356-9 CODEN: CHTPBA; ISSN: 0009-4374, 1968, XP009033121.
Svoboda, Jiri et al.: Synthesis of ‘!Benzothieno’3,2-b!furan-A New Fused Benzoheterocyclic System: Collection of Czechoslovak Chemical Communications, 58(12), 2983-6 CODEN: CCCCAK; ISSN: 0010-0765, 1993, XP009033071.
Vaidya, V. P. et al: “Studies in Benzofurans: Part XIV. Synthesis of Benzofuran and Benzofuro′3,2-b!Furan Derivatives of Pharmacological Interest” Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 22b(5), 462-4 CODEN: IJSBDB; ISSN: 0376-4699, 1983, XP009033083.
Karche, Navnath P. et al: “Electronic Effects in Migratory Groups. ‘1,4!-Versus ’1,2!-Rearrangement in Rhodium Carbenoid Generated Bicyclic Oxonium Ylides” Journal of Organic Chemistry, 66(19), 6323-6332 CODEN: Joceah; ISSN: 0022-3263, 2001, XP002286808.
Boschelli, Diane et al: “Inhibition of E-Selection-, ICAM-1-, and VCAM-1-Mediated Cell Adhesion by Benzo'b!thiophene-, Benzofuran-, Indole-, and Naphthalene-2-Carboxamides: Identification of PD 144795 as an Antiinflammatory Agent” Journal of Medicinal Chemistry, 38(22), 4597-614 CODEN: JMCMAR; ISSN: 0022-2623, 1995, XP002286757.
Boschelli, Diane et al: “3-Alkoxybenzo'B!thiophene-2-Carboxamides as Inhibitors of Neutrophil-Endothelial Cell Adhesion” Journal of Medicinal Chemistry, 37(6), 717-18 CODEN: JMCMAR; ISSN: 0022-2623, 1994, XP002286755.
Svoboda, Jiri et al: “Application of Magnesium Alkoxides to Syntheses of Benzoheterocyclic Compounds” Collection of Czechoslovak Chemical Communications, 58(3), 592-9 CODEN: CCCCAK; ISSN: 0010-0765, 1993, XP001194423.
Norris, Robert et al: Some Studies on the Reversibility of the Association Step in SRN1 Reactions: Australian Journal of Chemistry, 38(7), 1107-16 CODEN: AJCHAS; ISSN: 0004-9425, 1985, XP009033098.
Beck James: “‘1!Benzothieno’3,2-b!Furan Derivatives” Journal of Heterocyclic Chemistry, 12 (5), 1037-8 CODEN: JHTCAD; ISSN: 0022-152X, 1975, XP002286809.

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