Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-10-26
2011-10-18
Saeed, Kamal (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S345000, C514S383000, C514S393000, C514S418000, C514S443000, C514S456000, C514S521000, C514S568000, C546S141000, C546S290000, C548S262400, C548S302100, C548S512000
Reexamination Certificate
active
08039484
ABSTRACT:
Diaryl ethers in which one of the aryl groups is a phenyl fused to a cycloalkyl or heterocyclic ring, to which is attached an acetic acid group, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that often accompany this disease, including insulin resistance, obesity and lipid disorders.
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patent: 2003/0181494 (2003-09-01), Neogi et al.
patent: 2005/0171104 (2005-08-01), Rahimi-Ghadim et al.
Shinkai, “Novel antidiabetic agents”, Exp. Opin Ther. Patents (2000), vol. 10, pp. 59-66.
Supplementary European Search Report re EP 07839789, dated Nov. 2, 2010.
Ge Min
Lin Songnian
Walsh Shawn P.
Yang Lihu
Zhou Changyou
Durette Philippe L.
Merck Sharp & Dohme Corp.
Saeed Kamal
Struse Heidi M.
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