Antidiabetic 3,4,5-trihydroxypiperidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 32, 514 42, 514222, 514226, 514236, 514241, 514252, 514256, 514318, 514326, 514328, 536 174, 536 187, 536 23, 544 55, 544 586, 544 63, 544 96, 544 98, 544216, 544238, 544332, 544406, 546116, 546213, 546214, 546193, 546219, 546220, 546194, 546242, 546243, 546197, 546200, 546201, 546208, 546209, 546212, A61K 3170, C07D21146

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046394362

ABSTRACT:
The invention includes certain 3,4,5-trihydroxypiperidine compounds, methods for their preparation, compositions containing said 3,4,5-trihydroxypiperidine compounds and methods for the use of said compounds and compositions.
The subject matter of the invention is useful against diabetes, hyperlipaemia and adiposity as well as in animal nutrition.

REFERENCES:
patent: 4065562 (1977-12-01), Ohata et al.
patent: 4182767 (1980-01-01), Murai et al.
patent: 4533668 (1985-08-01), Matsumura et al.
Chemical Abstracts, 66: 65781n (1967), [Hanessian, S., Chem. Ind., 1966 (51), 2126-7].
Saeki, H. et al., Chem. Pharm. Bull., 16(5), 962 (1968).
House, H., Modern Synthetic Reactions, W. A. Benjamin, New York, 1965, pp. 42 and 197-199.
March, J., Advanced Organic Chemistry, McGraw Hill, New York, 1968, p. 331.

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