Antidepressant substituted hexahydro benzopyrano [3,2-c] pyridin

Details Antidepressant substituted hexahydro benzopyrano [3,2-c] pyridin Antidepressant substituted hexahydro benzopyrano [3,2-c] pyridin

1978-06-23

1980-05-06

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

542404, 546 48, 546 63, 546216, 546221, A61K 31445, C07D49118

Patent

active

042017831

ABSTRACT:
Substituted hexahydro benzopyrano [3,2-c] pyridines, useful as antidepressants, have the formula ##STR1## where R is hydrogen or a saturated or unsaturated, linear or branched, lower alkyl, or an aralkyl, acyl, dialkylaminoalkyl, carbonylalkyl, alkoxycarbonyl, haloalkoxycarbonyl or aryl radical; R.sub.1 is hydrogen, halogen, or lower alkoxy; R.sub.2 is hydrogen or halogen; R.sub.3 is hydrogen, halogen, lower alkyl, alkoxy nitro or amino, or forms naphthalene with R.sub.4 and the benzene ring; R.sub.4 is hydrogen, a halogen, or forms naphthalene with R.sub.3 and the benzene ring; R.sub.5 is hydrogen, lower alkyl, or aralkyl.

REFERENCES:
patent: 3673194 (1972-06-01), Morlock et al.
patent: 4070360 (1978-01-01), Ten Broeke et al.
Sammour, A. et al., Indian J. Chem., 12, 51-53 (1974).

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