Antidepressant heteroarylaminoalkyl derivatives of naphthyl-mona

Details Antidepressant heteroarylaminoalkyl derivatives of naphthyl-mona Antidepressant heteroarylaminoalkyl derivatives of naphthyl-mona

1995-03-29

1995-12-05

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514269, 514317, 514318, 514319, 544333, 544405, 546184, 546194, 546205, 546206, 546236, A61K 31495, A61K 31505, A61K 31445

Patent

active

054729661

ABSTRACT:
Certain aminoalkyl derivatives of naphthyl-piperidines and tetrahydro-pyridines of Formula (I) are useful antidepressant agents. ##STR1## The symbol (Aryl) denotes phenyl, naphthyl, pyridinyl, pyrimidinyl and pyrazinyl ring systems with n being an integer of 2-4.

REFERENCES:
patent: 5166156 (1992-11-01), Lavielle et al.
patent: 5250544 (1993-10-01), Lavielle et al.
patent: 5292711 (1994-03-01), Nishimura et al.
patent: 5292761 (1994-03-01), Lavielle et al.
Glennon et al, "5-HT.sub.1D Serotonin Receptors: Results of a Structure-Affinity Investigation," Drug Development Research, 22:25-36 (1991).

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