Anticonvulsive imidazoline-2,4-diones and process for making

Details Anticonvulsive imidazoline-2,4-diones and process for making Anticonvulsive imidazoline-2,4-diones and process for making

1996-08-21

1998-10-06

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514391, 5483171, 5483205, 5483211, A61K 31415, C07D23374

Patent

active

058176853

ABSTRACT:
Anticonvulsive compounds and compositions, of the formula ##STR1## in which X is a C.sub.1-4 -alkyl, trifluoromethyl, or halogen residue, Y is hydrogen or halogen, n is 0 or 1, and m is 0 or a cardinal number from 1 to 4, and its pharmacologically acceptable acid addition salts.

REFERENCES:
patent: 5545652 (1996-08-01), Itoh et al.
Idi et al, "A Carbon--13NMR Study of, etc" CA 85:191674, 1976.
Waser et al, "Development of New Antiepileptic Drugs, etc" CA 88:69084, 1978.
H.E. Zaugg and D.L. Arendsen-Synthesis of Fused Hydantoins by Intramolecular Amidolkylation pp. 803-806 (1974).
Harvey J. Kupferberg--Strategies for identifying and developing new anticonsulvant drugs. pp. 132-138 (1992).

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