Anticonvulsant valproic acid salts

Details Anticonvulsant valproic acid salts Anticonvulsant valproic acid salts

1986-05-16

1987-10-13

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

26050111, 514565, 548344, 562433, 562553, 562560, 562562, 562606, A61K 31195, C07D10104

Patent

active

046999272

ABSTRACT:
Water-soluble valproic acid salts, consisting of reaction products of valproic acid with at least one basic amino-acid, the latter being preferably selected from the group comprising arginine, lysine, histidine, ornithine and glycine.

REFERENCES:
Kovach, I. et al., J. Pharm. Sci., 64(6), 1070-1071 (1975).
HRC Report: Acute Oral Toxicity of L-Lysine Valproate (Valprolyn Galephar) in the Mouse, Davies, J. et al., Huntingdon Research Centre, Huntingdon, England, 4/27/82.
HRC Report: Acute Oral Toxicity of L-Lysine Valproate (Valprolyn Galephar) in the Rat, Davies, J. et al., Huntingdon Research Centre, Huntingdon, England 4/26/82.
Chemical Abstracts, 43:4710a (1949) [Neuberg et al., Arch. Biochem., 19, 149-61 (1948)].
Chemical Abstracts, 82:103136w (1975) [Japan. Kokai 74, 81,517, 8/6/74, Kawata].
Chemical Abstracts, 91:125092s (1979) [Ger. Offen. 2, 802,195, 7/26/79, Onczul].
Chemical Abstracts, 94:36376g (1981) [Ger. Offen. 3,017,032, 11/13/80, Christiansen].
Rohdewald, P. et al., Thermochimica Acta, 49, 101-110 (1981).
Chemical Abstracts, 89:122899h (1978) [Egli, M. et al., Schweiz. Rundsch. Med./Prax., 1978, 67 (26), 974-80].
Klotz, U. et al., International Journal of Clinical Pharmacology, Therapy and Toxicology, vol. 18, No. 10, pp. 461-465 (1980).
Sorel, L. et al., Acta Neurol. Belg., vol. 81, pp. 283-290 (1981) (abstract).

Affiliated with

Also associated with

Rating

Anticonvulsant valproic acid salts does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anticonvulsant valproic acid salts, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anticonvulsant valproic acid salts will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-411689