Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-03-28
1990-02-06
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514217, 514304, 514389, A61K 3144, A61K 3155, A61K 31415
Patent
active
048988600
ABSTRACT:
An anticonvulsant composition comprising as an active ingredient an amount effective for controlling seizures in mammals of a compound selected from the group consisting of dextromethorphan and other non-narcotic, non-addictive, low-toxicity compounds that bind to the same central nervous system sites as dextromethorphan. The composition may also contain an antiepileptic hydantoin, which is potentiated by said compound.
REFERENCES:
Chemical Abstracts (1984) 16449H.
High-Affinity DM Binding Sites in Guinea Pig Brain, Craviso, G. L. and Musacchio, J. M., Mol. Pharmacol., 23:619-628 (1982).
High-Affinity DM Binding Sites in Guinea Pig Brain, Craviso, G. L. and Musacchio, J. M., Mol. Pharmacol., 23:629-640 (1982).
Merck Index, 10th Ed., No. 6727.
Merck Index, 10th Ed., No. 1127.
Musacchio Jose M.
Tortella Frank C.
Friedman Stanley J.
New York University
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