Anticoagulant substance

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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424183, A61K 31725

Patent

active

044382618

ABSTRACT:
Partially depolymerized heparin products having particular analyzable reducing end groups, a process for their preparation and their use as anticoagulants and antithrombotics.

REFERENCES:
patent: 3766167 (1971-03-01), Lasker et al.
patent: 4281108 (1981-07-01), Fussi
patent: 4303651 (1981-12-01), Lindahl et al.
Barrowcliffe et al., Brit. Journal of Haematology, 1979, vol. 41, pp. 578-583.
Rosenberg & Lun Lam, Correlation Between Structure and Function of Heparin, Prc. Natl. Acad. Sci. U.S.A., vol. 76, No. 3, pp. 1218-1222, Mar. 1979.
Lindahl et al., Proc. Natl. Acad. Sci. U.S.A., vol. 76, No. 7, pp. 3198-3203, Jul. 1979, Biochemistry.
Hirano et al., Connective Tissue Research, 1975, vol. 3, pp. 73-79, Gordon and Breach Science Publishers, Ltd.
Shively et al., Biochemistry, vol. 15, No. 18, 1976, pp. 3932-3942.
The Merck Index, 7th Edition, p. 511, Merck & Co., Inc., (1960).

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