Anticoagulant and fibrinolytic therapy using p38 MAP kinase...

Details Anticoagulant and fibrinolytic therapy using p38 MAP kinase... Anticoagulant and fibrinolytic therapy using p38 MAP kinase...

2007-10-02

2007-10-02

Lilling, Herbert J. (Department: 1657)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S094640, C514S012200, C514S165000, C514S218000, C514S233200, C514S235800, C514S243000, C514S253010, C514S262100, C514S301000, C514S314000, C514S319000, C514S456000, C514S457000

Reexamination Certificate

active

11009480

ABSTRACT:
Disclosed are methods for a treating a disease or condition relating to blood coagulation and fibrinolysis using p38 MAP kinase inhibitors.

REFERENCES:
patent: 6319921 (2001-11-01), Cirillo et al.
patent: 6358945 (2002-03-01), Breitfelder et al.
patent: 6670357 (2003-12-01), Leftheris et al.
patent: WO 00/25791 (2000-05-01), None
patent: WO 00/43384 (2000-07-01), None
patent: WO 01/30778 (2001-05-01), None
patent: WO 01/37837 (2001-05-01), None
Branger, J., et al; Inhibition of coagulation, fibrinolysis and endothelial cell activation of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia. Blood, Jun. 1, 2003, vol. 101, No. 11, pp. 4446-4448.
Murdoch, C., et al; Chemokine receptors and their role in inflammation and infectious diseases, Blood, vol. 95 No. 10 May 15, 2000 pp. 3032-3043.
Marin, V. et al; The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment. Blood, Aug. 1, 2001, vol. 98, No. 3, pp. 667-673.

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