Anticoagulant agents

Details Anticoagulant agents Anticoagulant agents

1999-01-25

2000-12-12

Low, Christopher S. F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564336, 564374, C07C25718

Patent

active

061601764

ABSTRACT:
This invention relates to a compound of the Formula I

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patent: 5863929 (1999-01-01), Klimkowski
Derwent Abstract of WO 96/25426, 1996.
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Asghar, S. S., et al., "Inhibition of Cir, Cis and Generation of Cis by Amidino Compounds," Biochimica et Biophysica Acta, 317, 539-548, (1973).
Asgar, S. S., et al., "Human Plasma Kallikreins and Their Inhibition by Amidino Compounds," Biochimica et Biophysica Acta, 438, 250-264, (1976).
Bajusz, S., "Interaction of Trypsin-like Enzymes wth Small Inhibitors," Symposia Biologica Hungarica, 25, 277-298, (1984).
Shutske G. M., et al., "A Novel Synthesis of 3-Amino-1,2-Benzisoxazoles--an Entry into the Isoxazolo[3,4,5-ef] [1,4]benzoxazepine Ring System," J. Heterocyclic Chem., 26, 1293-1298, (1989).
Reguera, R., et al., "Putrescine Uptake Inhibition by Aromatic Diamidines in Leishmania Infantum Promastigotes", Biochem. Pharm., 47, 1859-1866, (1994).

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