Anticholinergic compounds

Details Anticholinergic compounds Anticholinergic compounds

1969-02-10

1984-08-21

Miller, Edward A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21170

Patent

active

044670958

ABSTRACT:
Glycolic esters, useful as anticholinergic drugs, have the formula ##STR1## wherein R.sub.1 is selected from the class consisting of phenyl and cyclopentyl; R.sub.2 represents a hydrocarbon radical of 3 to 6 carbon atoms; Z is selected from the class consisting of --CH.sub.2 --, --CH.sub.2 CH.sub.2 -- and --CH.sub.2 CH.dbd. and R.sub.3 represents an azacyclic ring selected from the class consisting of 1-methyltetrahydropyridine, 1-methyl-3-pyrroline, quinuclidine, 2-tropidine and 1-azabicyclo[2.2.2]oct-2-ene.

REFERENCES:
patent: 3399206 (1968-08-01), Kuhnis et al.
patent: 3627775 (1971-12-01), Hubner et al.
patent: 3786059 (1974-01-01), Walker et al.
patent: 3879556 (1975-04-01), Walker et al.
Burger, "Drugs Affecting the Central Nervous System", vol. 2, pp. 128-132 and 139, Marcel Dekker, Inc., (Mar. 1968), N.Y.
Mutschler, Arzneimittel-Forsch., 16(1), 73-5, (1966), [and abstract thereof; C.A., 65, 1224e, (1966)].
Morrison and Boyd, Organic Chemistry, p. 626, Allyn & Bacon, Inc., (1959), Boston.

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