Anticholesteremic compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549329, 560 61, 560 60, 560 62, 560 45, 562470, 562471, 546290, 546303, 564182, 558241, 558257, C07C 6976, C07C 5948

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055301452

ABSTRACT:
Novel anticholesteremic compounds capable of reducing blood cholesterol levels. Also included in this invention are (i) intermediates from which the abovementioned anticholesteremic compounds can be prepared, and (ii) methods for preparing both the intermediates and the anticholesteremic compounds.

REFERENCES:
patent: 3674836 (1972-07-01), Creger
patent: 3707566 (1972-12-01), Creger et al.
patent: 4665226 (1987-05-01), Kearney
Stevens, T. J. et al Artery (Fulton, Mich.) (1983) 12(2) 81-94.
Sircar et al., "Phenylenebis(oxy)bix[2,2-dimethylpentanoic acid's: Agents That Elevate High-Density Lipoproteins,", J. Med. Chem 26:1020-1027, 1983.
Morishita et al., "Synthesis and Hypolipidemic Activity of 2-Substituted Isobutyric Acid Derivatives," J. Med. Chem. 31:1205-1209, 1988.

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