Antichlorinergic bronchodilators

Details Antichlorinergic bronchodilators Antichlorinergic bronchodilators

1979-03-05

1980-10-14

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26037625, 26037635, 26032636, 26032647, 424274, 546281, C07D20712, A61K 3140, A61K 3144

Patent

active

042281717

ABSTRACT:
Compounds of the formula ##STR1## where R.sup.1 and R.sup.2 are the same or different and are phenyl optionally substituted with a substituent selected from the group C.sub.1 and C.sub.6 alkyl, C.sub.1 and C.sub.6 alkoxy and halo; or C.sub.4 or C.sub.5 heterocyclic aryl, the heteroatom selected from the group oxygen, nitrogen and sulfur; R.sup.3 and R.sup.4 are the same or different and are C.sub.1 to C.sub.6 alkyl; m is the integer 2 through 5; and X is selected from the group methanesulfonate, benzenesulfonate, p-toluene-sulfonate, nitrate, chloride, bromide and iodide. Methods for preparing these compounds are also disclosed. The compounds of the present invention are useful as anticholinergic agents.

REFERENCES:
patent: 3091570 (1963-05-01), Biel
patent: 3094463 (1963-06-01), Biel
patent: 3138614 (1964-06-01), Arnsworth et al.
Kaguwata et al.; Chem. Abs., vol. 80:44017s (1974).
Kaguwata et al.; Chem. Abs., vol. 80:66588f (1974).
Takada et al.; Chem. Abs., vol. 80:66587e (1974).
Traversa et al.; Chem. Abs., vol. 85:116533k.

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