Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof
Patent
1978-04-24
1980-11-25
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Dentifrices
Ammonia, amine, or derivative thereof
2603451, 260456R, 546184, 546243, 546246, 546248, 562590, 568853, A61K 722, C07D21114
Patent
active
042358752
ABSTRACT:
Novel alkyl 1-(hydroxyalkyl)piperidines and acid addition salts thereof, useful as inhibitors of dental plaque and therefore also useful against dental caries and periodontitis, are disclosed. Methods of making same, orally-acceptable compositions thereof, a method of treating therewith, and important and novel intermediates for the production thereof are also disclosed.
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Clark et al., The Encyclopedia of Chemistry, Reinhold Pub. Co., New York, 1957, pp. 683-684.
Weisgerber, D., Letter from Chemical Abstracts Service to G. W. Hueschen, 8/29/79.
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Morrison, R., et al., Organic Chemistry, 2nd Edition, Allyn and Bacon, Boston, 1966, pp. 137 and 1187.
Abramo Aina L.
Hernestam Sven E. H.
Johansson Hans-Bertil
Willard Lars O.
A.B. Ferrosan
Hueschen Gordon W.
Jiles Henry R.
Schwartz Richard A.
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