Anticaries dentifrice

Details Anticaries dentifrice Anticaries dentifrice

1990-03-27

1991-06-25

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

424 52, 424 55, A61K 716, A61K 718, A61K 724

Patent

active

050265393

ABSTRACT:
An anti-caries composition has a source of hydrogen citrate ions, preferably an alkali metal hydrogen citrate salt, an oxalate salt and an orally acceptable excipient, and optionally further comprises an ionic fluorine-containing compound. The composition may be in the form of dentifrice when silica is the preferred abrasive, or a mouthwash.

REFERENCES:
patent: 4057621 (1977-11-01), Pashley et al.
patent: 4645662 (1987-02-01), Nakashima et al.
Duke et al., CA.109:215748e (1988), of Caries Res. 22(6):350-352 (1988).
Duke et al, CA.105:120543n (1986), of EP 188313, Jul. 23, 1986, 14 pp.
Pashley et al, CA.102:31928p (1985), J. Peurdent. 55(9):522-525 (1984).
Pashley et al, CA.88:55104j (1978), of U.S. 4,057,621, Nov. 8, 1977.
Lion Corp., CA102:172445g (1985), of JPN 6004117, Jan. 10, 1985.
Schott et al, CA.101:157538h (1984), of J. Pharm. Sci. 73(6):793-(1984).
Just et al., CA.88:8865y (1978), of Ger. Ofc. 2,615,698, Oct. 20, 1977.

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