Anticancer (IV) complexes for oral administration and a method o

Details Anticancer (IV) complexes for oral administration and a method o Anticancer (IV) complexes for oral administration and a method o

1998-08-14

1999-12-07

Geist, Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

556136, 549206, C07F 1500

Patent

active

059986484

ABSTRACT:
Platinum (IV) complexes for oral administration represented by the structural formula ##STR1## where A--A is a symmetrical diamine that can chelate to platinum and is selected from the group consisting of ethylene diamine, t(.+-.)-1,2-diaminocyclohexane, 2,2-dimethyl-1,3-propanediamine, cyclohexane-1,1-dimethaneamine and tetrahydro-4H-pyran-4,4-dimethaneamine; and R is propionyl, butyryl or valeryl. These complexes are useful in the treatment of cancer.

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