Anticancer agents and methods of manufacture

Details Anticancer agents and methods of manufacture Anticancer agents and methods of manufacture

1980-01-31

1981-08-11

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260366, 260429R, C07D30900, C07D31100, C07F 1500

Patent

active

042833426

ABSTRACT:
A therapeutic metal coordination compound, particularly useful as an anticancer agent, which is the reaction product of a hydroxy quinone and a cisplatinum (II) compound substituted with chloro ligands and ammonia or derivatized ammonia ligands and the process for its manufacture.

REFERENCES:
patent: 2895967 (1959-07-01), Straley et al.
patent: 3192236 (1965-06-01), O'Connell
patent: 4169846 (1979-10-01), Kidani et al.
patent: 4200583 (1980-04-01), Kidami et al.
Yolles et al., Acta Pharmaceutica Suecia, 15, 382-388 (1978).
Chemical Abstracts, 89 99746v (1978).
Chemical Abstracts, 85 28554n (1976).
Chemical Abstracts, 84 31164v (1976).

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