Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1996-07-03
1999-08-03
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514559, 514558, 514560, A61K 3121, A61K 3120
Patent
active
059326131
ABSTRACT:
A method of treating cancer with a pharmaceutical composition containing a pine root (Deutero Mycetes) fungal metabolite or an analog or derivative thereof.
REFERENCES:
Yamakawa et al., "Stereoselective Total Synthesis of (.+-.)-Eremofortin B, A Sesquiterpenoid Mycotoxin of Penicillium roqueforti", Chem. Letters, The Chem. Soc. of Japan, pp. 929-932 (1981).
Tirilly et al., "A Fungitoxic Sesquiterpene from Hansfordia Pulvin ATA", Phytochem., 22(9):2082-83 (1983).
Kim et al., "A Brassinolide-Inhibitor KM-01, Its Isolation and Structure Elucidation from a Fungus Drechslera avenae", Tetrahedron Letters, 35(11):1731-34 (1994).
Yoshizawa et al., "Incorporation of .sup.13 C-Labelled 5-epi-Aristolochene into Capsidiol in Green Pepper Seedlings", Biosci. Biotech. Biochem., 58(2)305-308 (1994).
Abstracts, Dictionary of Natural Products on CD-ROM, Release 3:2, pp. 1-8 (1995).
Kim et al., "Biological Activity of Brassinosteroid Inhibitor KM-01 Produced by a Fungus Drechslera avenae", Biosci. Biotech. Biochem., 59(8)1394-97 (1995).
Gallagher Rex T.
Jiang Wei-Dong
Jiang Zhi-Dong
Goldberg Jerome D.
Millennium Pharmaceuticals Inc.
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