Anticalins

Details Anticalins Anticalins

2007-07-31

2007-07-31

Kemmerer, Elizabeth (Department: 1649)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

C530S350000

Reexamination Certificate

active

09509444

ABSTRACT:
The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using genetic engineering methods. A like immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.

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