Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1989-03-09
1991-02-05
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 49, 424 57, A61K 916, A61K 918
Patent
active
049903284
ABSTRACT:
Disclosed are oral compositions containing phosphocitrate to provide improved anticalculus activity.
REFERENCES:
patent: 4515772 (1985-05-01), Parran et al.
patent: 4518430 (1985-05-01), Brown et al.
patent: 4753652 (1988-06-01), Langer et al.
Howard, J. E., "Studies on Urinary Stone Formation a Saga of Clinical Investigation", Johns Hopkins Medical Journal, 139 (6), 1976, pp. 239-252.
Gimenez et al., "Phosphocitrate Prevents Phosphate Induced Loss of Renal Function in Experimental Aremia", Clinical Research, 29 (2), 1981, p. 539A.
Tew et al., "The Effects of Phosphocitrate on Experimentally Induced Nephro Calcinosis", Kidney International, 19 (1) 1981, p. 117.
Mohl Douglas C.
Rose Shep K.
Schaeffer Jack D.
The Procter & Gamble & Company
Zerby Kim William
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