Anticalculus compositions

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424 49, 424 57, A61K 916, A61K 918

Patent

active

049903284

ABSTRACT:
Disclosed are oral compositions containing phosphocitrate to provide improved anticalculus activity.

REFERENCES:
patent: 4515772 (1985-05-01), Parran et al.
patent: 4518430 (1985-05-01), Brown et al.
patent: 4753652 (1988-06-01), Langer et al.
Howard, J. E., "Studies on Urinary Stone Formation a Saga of Clinical Investigation", Johns Hopkins Medical Journal, 139 (6), 1976, pp. 239-252.
Gimenez et al., "Phosphocitrate Prevents Phosphate Induced Loss of Renal Function in Experimental Aremia", Clinical Research, 29 (2), 1981, p. 539A.
Tew et al., "The Effects of Phosphocitrate on Experimentally Induced Nephro Calcinosis", Kidney International, 19 (1) 1981, p. 117.

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