Antibotic A80577 and process for its production

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549414, 549315, 549317, A61K 3135, A61K 31365, C07D30906

Patent

active

048762733

ABSTRACT:
New polyether antibiotic A80577, its acyl ester and alkyl ether derivatives, and salts thereof, are useful antibacterial agents and increase feed-utilization efficiency in animals. Methods of making A80577 by culture of Actinomadura verrucosospora, NRRL 18236, and compositions containing an A80577 compound also are provided.

REFERENCES:
patent: 3839557 (1974-10-01), Raun
patent: 4279894 (1981-07-01), Davies et al.
patent: 4443471 (1984-04-01), Davies et al.
Davies et al., "Structure of Antibotic M139603; X-ray Crystal Structure of the 4-Bromo-3,5-dinitrobenzoyl Derivative", J. Chem. Comm., 1073 (1981).
Keller-Juslen et al., "Tetronomycin, a Novel Polyether of Unusual Structure", J. Antibiotics, 142-150 (1982).

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