Antibody testing system

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Calorimeter

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422 57, 422 58, 422101, 435 71, 435301, 435805, G01N 3353

Patent

active

054198704

ABSTRACT:
A device for performance of ligand-receptor assay methods for determining the presence of a liquid. The preferred ligand-receptor pair are antigen-antibody pairs. The device has a membrane having the receptor physically bound to its surface. The membrane is disposed at the top of a body member, and is affixed thereto by means for attaching, which is preferably a cap with a funnel depression. A porous means is disposed below the membrane to absorb liquid. Substantially all of the top surface of the membrane is exposed. The receptor site typically occupies only a portion of the top of the membrane, and in a preferred embodiment, a funnel member releasably attaches to the cap, thereby conveying the sample through only that area of the membrane having the receptor site. The device has a piston means disposed inside the body member, and in air-tight seal with the body member. Means to actuate the piston means are disposed outside the body member. The piston means creates a region of reduced pressure to urge the sample through the membrane.

REFERENCES:
patent: 4789526 (1988-12-01), Matkovich
patent: 4797259 (1989-01-01), Matkovich et al.
patent: 4797260 (1989-01-01), Parker
patent: 4874691 (1989-10-01), Chandler
patent: 4908319 (1990-03-01), Smyczek et al.

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