Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-02-14
2006-02-14
Turner, Sharon L. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387300, C530S388100, C530S389100, C435S326000, C435S328000
Reexamination Certificate
active
06998467
ABSTRACT:
The present invention describes the identification, isolation, cloning, and determination of the Alzheimer Related Membrane Protein (ARMP) gene on chromosome 14 and a related gene, E5-1, on chromosome 1. Normal and mutant copies of both genes are presented. Transcripts and products of these genes are useful in detecting and diagnosing Alzheimer's disease, developing therapeutics for treatment of Alzheimer's disease, as well as the isolation and manufacture of the protein and the construction of transgenic animals expressing the mutant genes.
REFERENCES:
patent: 6210919 (2001-04-01), St. George-Hyslop et al.
patent: 6531586 (2003-03-01), St. George-Hyslop et al.
Fraser Paul E.
Rommens Johanna M.
St. George-Hyslop Peter H.
Darby & Darby
HSC Research and Development Limited Partnership
The Governing Council of the University of Toronto
The Hospital for Sick Children
Turner Sharon L.
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