Antibody recognizing endothelial cell ligand for leukocyte CR3

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds antigen or epitope whose amino acid sequence is...

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4241501, 4241781, 4241411, 4241521, 5303879, 5303884, A61K 3940, A61K 39395

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active

057924570

ABSTRACT:
Peptides and antibodies which will inhibit the reaction between the RGD tripeptide of FHA and the integrin receptors of endothelial cells and their utility as therapeutic agents and a method of increasing the permeability of the blood-brain barrier using an antibody to the Arg-Gly-Asp (RGD) region of filamentous hemagglutinin (FHA) are described.

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