Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds antigen or epitope whose amino acid sequence is...
Patent
1995-06-06
1998-08-11
Hutzell, Paula K.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds antigen or epitope whose amino acid sequence is...
4241501, 4241781, 4241411, 4241521, 5303879, 5303884, A61K 3940, A61K 39395
Patent
active
057924570
ABSTRACT:
Peptides and antibodies which will inhibit the reaction between the RGD tripeptide of FHA and the integrin receptors of endothelial cells and their utility as therapeutic agents and a method of increasing the permeability of the blood-brain barrier using an antibody to the Arg-Gly-Asp (RGD) region of filamentous hemagglutinin (FHA) are described.
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Masure H. Robert
Tuomanen Elaine
Hutzell Paula K.
Krikorian Jacqueline G.
The Rockefeller University
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