Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-02-14
2006-02-14
Le, Long V. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S007930, C435S007940, C436S512000, C436S513000
Reexamination Certificate
active
06998241
ABSTRACT:
The invention provides methods for identifying antibody preparations that can form a pair of antibodies that optimally detect a target antigen, for example, in a sandwich immunoassay. These methods provide high affinity and epitope-specific antibodies.
REFERENCES:
patent: 5026653 (1991-06-01), Lee et al.
patent: 5217871 (1993-06-01), Petersen et al.
patent: 5426029 (1995-06-01), Rittershaus et al.
patent: 5554339 (1996-09-01), Cozzette et al.
patent: 6406920 (2002-06-01), Davis et al.
Andersson, K..,et al., “Identification and optimization of regeneration conditions for affinity-based biosensor assays, a multivariant cocktail approach”,Anal. Chem., 71, (1999),2475-2481.
Azimzadeh, A..,et al., “Operational aspects of antibody affinity constants measured by liquid-phase and solid-phase assays”,J. Mol. Recogn., 5, (1992),9-18.
Babu, B..R.,et al., “L-Arginine binding to nitric oxide synthase, the role of H-bonds to the non-reactive guanidinium nitrogens”,J. Biol. Chem., 274, (1999),25218-25226.
Burks, A..W.,et al., “Food allergies in children”,Curr. Prob. Pediatr., 23, (1993),230-252.
Crockson, R..A.,et al.,“Time sequence of acute phase reactive proteins following surgical trauma”,Clin. Chim. Acta, 66, (1966),435-441.
Dubs, M..C.,et al., “Mapping of viral epitopes with conformationally specific monoclonal antibodies using biosensor technology”,J. Chromatogr., 597, (1992),127-148.
Fagerstam, L..G.,et al., “Detection of antigen-antibody interactions by furface plasmon resonance, application to apitope mapping”,J. Mol. Regonit., 3, (1990),208-214.
Garman, S..C.,et al.,“Structure of the Fc fragment of human IgE bound to its high-affinity receptor FceRIa”,Nature, 406, (2000),259-266.
Heinrich, B..A.,et al.,“Respiratory diseases and allergies in two polluted areas in East Germany”,Environ. Health Perspect., 107, (1999),53-62.
Helm, B..A.,et al.,“Identification of the high affinity receptor binding region in human Immunoglobulin E”,J. Biol. Chem., 271, (1996),7494-7500.
Henry, A..J.,et al.,“Conformation of the isolated Ce3 domain of IgE and its complex with the high-affinity receptor, FceRI”,Biochemistry, 39, (2000),7406-7413.
Henry, A..J.,et al.,“Participation of the N-terminal region of Ce3 in the binding of human IgE to its high-affinity receptor FceRI”,Biochemistry, 36, (1997),15568-15578.
Jansen, J..J.,et al., “Prevalence of food allergy and intolerance in the adult Dutch population”,J. Allergy Clin. Immunol., 93, (1994),446-456.
Karlsson, R..,et al., “Analysis of active antibody concentration, separation of affinity and concentration parameters”,J. Immunol. Methods, 166, (1993),75-84.
Luhr, T..A.,et al., “Development of a high-sensitivity C-reactive protein assay”,IVD Technology, 6, Mar./Apr. Issue,(2000).
Luo, J..,et al.,“Determination of interaction mechanism of sensorgrams by analysis of binding kinetics”,J. Protein Chem., 18, (1999),709-719.
MacKenzie, C..R.,et al.,“Analysis by surface plasmon resonance of the influence of valence on the ligand binding affinity and kinetics of an anti-carbohydrate antibody”,J. Biol. Chem., 271, (1996),1527-1533.
McDonnell, J..M.,“Surface plasmon resonance towards an understanding of the mechanisms of biological molecular recognition”,Current Opinion Chemical Biology, 5, (2001),572-577.
Metzger, H..,“The receptor with high affinity for IgE”,Immunol. Rev., 125, (1992),37-48.
Myszka, D.., “Kinetic analysis of macromolecular interactions using the surface plasmon resonance biosensors”,Curr. Opin. Biotechnol., 8, (1997),50-57.
Nygren, H..,et al., “Kinetics of antibody binding to solid-phase immobilized antigen, effect of diffusion rate limitation and steric interaction”,J. Immunol. Methods, 101, (1987),63-71.
O'Shannessy, D..,et al.,“Immobilization chemistries suitable for use in the BIAcore surface plasmon resonance detector”,Biochem., 205, (1992),132-136.
Ohlson, S..,“Detection and characterization of weak affinity antibody antigen recognition with bimolecular interaction analysis”,J. Mol. Recognit., 10, (1997),135-138.
Perez de la Lastra, J..M.,et al.,“Epitope mapping of 10 monoclonal antibodies against the pig analogues of human membrane cofactor protein (MCP)”,Immunology, 96, (1999),663-670.
Rich, R..L.,et al.,“Biacore J, a new platform for routine biomolecular interaction analysis”,J. Mol. Recognit., 14, (2001),223-228.
Ridker, P..M.,et al.,“Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men”,N. Engl. J. Med., 336, (1997),973-979.
Rifai, N..,et al.,“C-reactive protein, a new and strong predictor of cardiovascular disease”,Clin. Lab. News, Oct. issue,(2001), 12-14.
Robbio, L..L.,et al.,“Epitope mapping analysis of apolipoprotein B-100 using a surface plasmon resonance-based biosensor”,Biosens. Bioelectron., 16, (2001),963-969.
Roos, H..,et al.,“Thermodynamic analysis of protein interactions with biosensor technology”,J. Mol. Recognit., 11, (1998),204-210.
Steward, M..W.,et al.,“The importance of antibody affinity in the performance of immunoassays for antibody”,J. Immunol. Methods, 78, (1985),173-190.
Sutton, B..J. ,et al., “The Human IgE-network”,Nature, 366, (1993),421-428.
Tanford, C..,“The hydrophobic effect and organization of living matter”,Science, 200, (1978),1012-1018.
Cheu Jacob
Kimberly--Clark Worldwide, Inc.
Le Long V.
Schwegman Lundberg Woessner & Kluth P.A.
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