Antibody or antibody fragments specific for a protein of the...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387900, C530S388100, C530S389200

Reexamination Certificate

active

07067637

ABSTRACT:
The invention provides antibody and antibody fragments which specifically bind to novel members of the TGF-β family of proteins. The TFG-β family comprises proteins which function as growth and/or differentiation factors and which are useful in medical applications. Accordingly, the invention also applies to the production of said antibodies or antibody fragments and a diagnostic method for detecting said proteins of the TGF-β family.

REFERENCES:
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patent: 5801014 (1998-09-01), Lee et al.
patent: 0 222 491 (1987-05-01), None
patent: WO 93/16099 (1993-08-01), None
patent: 95/02552 (1996-01-01), None
Ganong. Review of Medical Physiology, 17thedition, 1995, Appleton & Lange, pp. 220, 446.
Creighton. Proteins, Structures and Molecular Principles, 1984, Freeman & Co., pp. 70-73.
Stratagene Catalog, 1988, p. 39.
The Journal of Biological Chemistry, Chang et al., vol. 269, No. 45, pp. 28227-28234 (Nov. 11, 1994).

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