Antibody-induced apoptosis

Details Antibody-induced apoptosis Antibody-induced apoptosis

1995-12-05

1998-07-21

Scheiner, Toni R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241331, 4241381, 4241411, 4241421, 435330, 435366, 5303873, 5303877, 53038815, 5303882, 53038822, 5303888, 53038885, 5303897, C07K 1630, C12N 512, A61K 39395

Patent

active

057831866

ABSTRACT:
Anti-Her2 antibodies which induce apoptosis in Her2 expressing cells are disclosed. The antibodies are used to "tag" Her2 overexpressing tumors for elimination by the host immune system. Also disclosed are hybridoma cell lines producing the antibodies, methods for treating cancer using the antibodies, and pharmaceutical compositions.

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