Antibody immunization therapy for treatment of atherosclerosis

Details Antibody immunization therapy for treatment of atherosclerosis Antibody immunization therapy for treatment of atherosclerosis

2003-10-03

2008-12-23

Haddad, Maher M. (Department: 1644)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S133100, C424S139100, C424S141100, C424S142100

Reexamination Certificate

active

07468183

ABSTRACT:
The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.

REFERENCES:
patent: 5494791 (1996-02-01), Cohen
patent: 5861276 (1999-01-01), Kwak et al.
patent: 5972890 (1999-10-01), Lees et al.
patent: 6225070 (2001-05-01), Witztum et al.
patent: 0433088 (1997-06-01), None
patent: WO9832845 (1998-07-01), None
patent: WO9842751 (1998-10-01), None
patent: WO9908109 (1999-02-01), None
patent: WO 99/18986 (1999-04-01), None
patent: WO9918986 (1999-04-01), None
patent: WO0132070 (2001-05-01), None
patent: WO0164008 (2001-09-01), None
patent: WO02080954 (2002-10-01), None
Tinahones et al. Journal of Lipid Research. 2005. 46:452-457.
The Merck Manual of Diagnosis and Therapy. 17th Edition. published by Merk Research Laboratories. 1999, pp. 1654-1659.
Li et al. Biochemistry 2000. 39:6296-6309.
Reff et al. Critical Review in Oncology/Hematology. 2001. 40:25-35.
Borrebaeck and Carlsson (2001) Curr. Opin. Pharmacol., 1:404-8.
Bruce et al. (1999) Int. J. Biochem. Cell Biol., 1409-20.
Caligiuri et al. (2002) J. Clin. Invest., 109:745-753.
Dimayuga et al. (2002) Arterioscl. Thromb. Vasc. Biol., 22:644-9.
Freigang et al. Arterioscl. Thromb. Vasc. Biol. (1998) 1973-82.
George et al. (1998) Atherosclerosis, 138:147-52.
Griffiths et al. (1994) EMBO J., 13:3245-3260.
Hammer et al. (1995) Aterioscl. Thromb. Vasc. Biol., 704-13.
Hoogenboom et al. (1992) J. Mol. Biol., 227:381-8.
Jovinge et al. (1997) Aterioscl. Thromb. Vasc. Biol., 17:2225-31.
Li et al. (2000) Biochemistry, 39 6296-6309.
McCafferty et al. (1990) Nature, 348:552-4.
Merck Manual of Diagnosis and Therapy (1999; 17th ed.) pp. 1656-1657.
Milstein and Kohler (1975) Nature, 256:495-7.
Neuberger et al. (1985) Nature, 314:268-70.
Palinski et al. (1989) Proc. Natl. Acad. Sci. USA, 86:1372-6.
Palinski et al. (1995) Proc. Natl. Acad. Sci. USA, 92:821-5.
Reff et al. (2001) Crit. Rev. Oncol/Hematol. 40:25-35.
Regnstrom et al. Atherosclerosis, 82:43-51.
Soderlind et al. (2000) Nature BioTechnol., 18:851-6.
Soderlind et al. (2001) Comb. Chem & High Throughput Screen, 4:409-16.
Steinberg et al. (1989) New England J. Med., 320:915-924.
Tinahones et al. (2005) J. Lipid Res. 46:452-7.
Valentinova et al. (1994) Biol. Chem., 651-8.
Zhou et al. (1998) J. Clin. Invest.,101:1717-25.

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