Antibody-containing oral composition for suppression of periodon

Details Antibody-containing oral composition for suppression of periodon Antibody-containing oral composition for suppression of periodon

1995-07-05

1998-06-02

Loring, Susan A.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds specifically-identified oligosaccharide structure

4241301, 4241501, 4241641, 5303891, 5303895, 5303875, 5303884, 514900, 514902, A61K 6097, A61K 39395, A61K 3940, C07K 1612

Patent

active

057595445

ABSTRACT:
An oral composition comprises an effective amount of an antibody obtained by immunizing an animal with an antigen comprised of at least one polysaccharide derived from the surface layer of periodontal disease associated bacteria. The at least one polysaccharide may be conjugated with polypeptides to further enhance the efficacy.

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Place, Deborah et al, Inf & Immun, 56(5): 1394-1398, May 1988.
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Bach et al., Immunology Today, vol. 14, No. 9, pp. 421-425 (1993).
Wilson et al., Infection and Immunity, vol. 59, No. 4, pp. 1544-1551 (1991).
Califano et al., Infection and Immunity, vol. 57, No. 5, pp. 1582-1589 (1989).

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