Antibody conjugates with two or more covalently linked FC region

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...

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4241791, 4241331, 4241361, 5303911, 5303913, 5303917, 5303919, A61K 3944, C07K 1702, C07K 1646

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active

056815662

ABSTRACT:
Synthetic antibody derivatives having at least two F regions covalently linked so as to enhance Fc activity for example effector recruitment. The use of such derivatives in the treatment of conditions where killing of cells is required for example cancer therapy. Methods for the preparation of derivatives are also described.

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