Antibody coated bacteria

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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23230B, 424 3, 424 85, 424 88, 435 7, G01N 3348, G01N 3350, G01N 3354

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active

042230055

ABSTRACT:
Process for identification and enumeration of B and T lymphocytes in an unseparated peripheral body sample comprises contacting the sample with two morphologically distinguishable bacteria, each of which is coated with an antibody specific to an antigen on one of the B or T cells. The presence of a B or a T cell is determined by rosette formation with the corresponding bacteria, as viewed under a microscope in a smear.

REFERENCES:
patent: 3553310 (1971-01-01), Csizmas
patent: 3639558 (1972-02-01), Csizmas
patent: 3873684 (1975-03-01), Fujita
patent: 3882225 (1975-05-01), Patel
patent: 3925018 (1975-12-01), Saunders
Molinaro, The J. of Immunol. vol. 114, No. 2, Pt. 1, Feb. 1975, pp. 908-910.
Molinaro, Nature, vol. 248, Apr. 5, 1974, pp. 515-517.
Zaalberg, Nature, vol. 202, Jun. 20, 1964, p. 1231.
Roitt, Essential Immunol., Blackwell Sci, Pub. London 2nd Ed. 2nd Print., 1974 pp. 43-49, 55-68.

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