Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1986-08-22
1989-09-12
Warden, Robert J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 25, 435 29, G01N 5300, C12Q 102
Patent
active
048659720
ABSTRACT:
An antibody-based bioassay for enzyme-inducing chemicals is disclosed. The percent induction of an enzyme or class of related enzymes in living cells by an enzyme-inducing chemical in a sample is determined before and after the addition to the sample of an antibody to the chemical. The concentration of the chemical before and after the addition of the antibody is determined by comparison to the percent induction by known concentrations of the chemical. This permits the determination of the concentration of the chemical in the sample.
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Johnson, "Multiple Forms of Cytochrome P-450: Criteria and Significance", in Reviews and Biochemical Toxicology, Hodgson et al., Eds. (Elsevier North Holland, Inc. 1979), pp. 1-26.
Benson Robert
Morrison Joyce L.
Warden Robert J.
Westinghouse Electric Corp.
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