Antibody/antigen determination method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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356246, 422 72, 436519, 436520, 436534, 436541, 436807, 436828, G01N 3354

Patent

active

045606471

ABSTRACT:
A method for the determination of antigens or antibodies in a fluid by incubation of particles, which have antigens on the surface, and antibodies, whereby either the antigens or the antibodies are of known specificity is described. This method comprises introducing the antigen/antibody complex into a container having a conical-shaped or keel-shaped bottom recess, whereby at least the recess of the container is coated with an immunoglobulin-building component which is directed against the antibodies. After centrifugation the amount of the sediment is determined, which indicates whether the antigen or antibody to be determined is present or not.

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patent: 4048298 (1977-09-01), Niswender
patent: 4130634 (1978-12-01), Molinaro
patent: 4148607 (1979-04-01), Bernoco
patent: 4154795 (1979-05-01), Thorne
patent: 4169138 (1979-09-01), Jonsson
patent: 4273756 (1981-06-01), Ling
patent: 4297104 (1981-10-01), Matte

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