Antibody and use thereof

Details Antibody and use thereof Antibody and use thereof

2004-12-03

2009-10-06

Nguyen, Bao-Thuy L (Department: 1641)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

C436S547000, C436S548000, C435S007100, C435S007920, C435S007930, C435S007940, C435S007950, C435S070100, C435S070200, C435S070210, C530S380000, C530S388200

Reexamination Certificate

active

07598351

ABSTRACT:
The anti-19P2 ligand monoclonal antibodies of the invention (in particular P2L-1Ca) have very high binding ability and can neutralize the arachidonic acid metabolite releasing activity of the 19P2 ligand. Therefore, they can be used, among others, as diagnostic, prophylactic and/or therapeutic agents for various diseases caused by some or other abnormality in the pituitary function modulating activity (e.g. prolactin secretion promoting activity), central nervous system modulating activity and pancreatic function modulating activity, among others, supposedly possessed by the 19P2 ligand.

REFERENCES:
patent: 887417 (1998-12-01), None
patent: WO 97/24436 (1997-07-01), None
patent: WO 98/49295 (1998-11-01), None
Wendy Strongin, “Sensitivity, Specificity, and Predictive Value of Diagnostic Tests: Definitions and Clinical Applications”, Laboratory Diagnosis of Viral Infections, Lennette, E., ed. Marcel Dekker, Inc. New York, (1993), pp. 211-219.

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