Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-01-18
2005-01-18
Chin, Christopher L. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S002000, C435S007920, C435S007940, C435S007950, C435S070200, C435S452000, C435S332000, C435S806000, C435S975000, C436S503000, C436S518000, C436S524000, C436S526000, C436S528000, C436S172000, C530S388200, C600S035000
Reexamination Certificate
active
06844164
ABSTRACT:
An antibody biding specifically to rat's acrosome reacted sperm is produced and hybridomas (FARS-91 and FARS-92 strains) capable of stably proliferating are obtained by fusing mouse spleen cells having a high antibody titer against rat's acrosome reacted sperm with mouse-origin myeloma cells and screening fused cells reacting strongly with rat's acrosome reacted sperm. From these hybridomas, monoclonal antibodies selectively binding to rat's acrosome reacted sperm can be obtained. Thus, a diagnostic method for evaluating fertility of rat's spermatozoa is presented.
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Araki Hiromasa
Hasegawa Michinori
Isaka Kiyotsugu
Kuwahara Yoshihiro
Browdy and Neimark PLLC
Chin Christopher L.
FUSO Pharmaceutical Industries, Ltd.
Grun James L.
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