Antibodies which specifically bind to proteins having tyrosine k

Details Antibodies which specifically bind to proteins having tyrosine k Antibodies which specifically bind to proteins having tyrosine k

1995-05-19

1997-08-19

Feisee, Lila

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Animal cell, per se, expressing immunoglobulin, antibody, or...

5303879, 5303881, 53038825, 53038826, 53038885, 5303891, 435338, C07K 1618, C12N 512

Patent

active

056587910

ABSTRACT:
The invention relates to antibodies which specifically bind to tyrosine kinase active proteins. The proteins have more than one protein kinase domain, and no SH2 domains. Exemplary proteins are the Janus Kinases, or "JAK1" and "JAK2". Both polyclonal and monoclonal antibodies are a part of the invention, as are hybridomas which produce the monoclonal antibodies.

REFERENCES:
patent: 4543539 (1985-09-01), Frackelton
Hunter, Cell 50:823-829, 1987.

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