Antibodies which specifically bind mcl-1 polypeptide

Details Antibodies which specifically bind mcl-1 polypeptide Antibodies which specifically bind mcl-1 polypeptide

1993-06-16

1995-11-28

Lacey, David L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

5303888, 53038885, 5303891, 5303897, C07K 1600, C07K 1630

Patent

active

054709555

ABSTRACT:
A gene, mcl-1, of the bcl-2 family is disclosed along with its nucleotide and amino acid sequence. Also disclosed are diagnostic methods of utilizing the mcl-1 nucleotide and polypeptide sequences. Antibodies which specifically bind the MCL-1 protein are also provided.

REFERENCES:
Spooner et al., Tibtech, 1990, 8:189, 1990.
Kozopas et al., PNAS, 1993, 90:3516.
Schlom, 1990, "Monoclonal Antibodies: They're More and Less Than You Think" In: Molecular and Cellular Research for Future Diagnosis and Therapy, S. Broder, Ed., Williams and Wilkins, Baltimore.

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