Antibodies which react with fibrinogen fragments E1, E2 and E3 a

Details Antibodies which react with fibrinogen fragments E1, E2 and E3 a Antibodies which react with fibrinogen fragments E1, E2 and E3 a

1993-12-15

1997-02-04

Chan, Christine

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 79, 435 792, 435 793, 435 794, 435 795, 435 13, 436518, 436536, 436537, 436538, 5303879, 53038825, 5303893, 5303911, 5303913, G01N 3353, C07K 1636

Patent

active

055996787

ABSTRACT:
The invention relates to antibodies which react with fibrinogen fragments E1, E2 and E3 raised by immunizing with a peptide. The invention also relates to assay methods for proteins containing an epitope which is common to fibrinogen fragments E1, E2 and E3 using these antibodies.

REFERENCES:
patent: 4960712 (1990-10-01), Theofilopoulos et al.
E. F. Plow et al., "Localization and Characterization of the Cleavage-associated Neoantigen Locus in the E Domain of Fibrinogen," The Journal of Biological Chemistry, vol. 254, No. 3, (Feb. 10, 1979) pp. 672-678.
J. P. Chen et al., "Radioimmunoassay of fragment E-related neoantigen: validation studies and clinical application," British Journal of Haematology, vol. 57, (1984) pp. 133-144.
P. W. Koppert et al., "A Monoclonal Antibody-Based Enzyme Immunoassay for Fibrin Degradation Products in Plasma," Thrombosis and Haemostasis, vol. 59, No. 2, (Apr. 8, 1988) pp. 310-315.
D. W. Chung et al., "Nucleotide Sequences of the Three Genes Coding for Human Fibrinogen," Adv. Exp. Med. Biol., vol. 281 (1990) pp. 39-48.
N. E. Kirschbaum et al., "A Unique Proteolytic Fragment of Human Fibrinogen Containing the A.alpha. Cooh-terminal Domain of the Native Molecule," The Journal of Biological Chemistry, vol. 265 (Aug. 15, 1990) pp. 13669-13676.
"Chemical Coupling of Peptides and Proteins to Polysaccharides by Means of Cyanogen Halides", Axen et al., Nature, 214:1302-1304 (1967).
"A Rapid, Simple, Sensitive Method for Measuring Fibrinolytic Split Products in Human Serum", Merskey et al., Proc. Soc. Exp. Biol. Med., 131:871-875 (1969).
"Peroxidase-Labeled Anibody--A New Method of Conjugation", Nakane et al., The Journal of Histochemistry and Cytochemistry, 22(12):1084-1091 (1974).
"Physical Biochemistry--Applications to Biochemistry and Molecular Biology", Freifelder, D., Saka W. H. Freeman and Company, p. 19:236(1976).
"Binding Phenomena of Isolated Unique Plasmic Degradation Products of Human Cross-linked Fibrin", Olexa et al., The Journal of Biological Chemistry, 254(11):4925-4932 (1979).
"Monoclonal Antibodies to a Synthetic Fibrin-Like Peptide Bind to Human Fibrin but No Fibrinogen", Hui et al., Science, 222:1129-1132 (1983).
"A Quantitative Automated Immunoassay for Fibrinogen/Fibrin Degradation Products", Schifreen et al., Clinical Chemistry, 31(9):1468-1473 (1985).
"Unreliabiltiy of Current Serum Fibrin Degradation Product (FDP) Assays", Gaffney et al., Thrombosis and Haemostasis, 53(3):301-302 (1985).
"Monoclonal Antibodies Against Fibrinogen, Fibrin and Their Fragments", Gaffney et al., Thrombosis and Haemostasis, 54(3):733-734 (1985).
"Plasma Assays of Fibrinogen/Fibrin Degradation Products and Their Clinical Relevance", Nieuwenhuizen, W., Fibrinogen 2. Biochemistry physiology and clinical relevance, Lowe et al., Eds., 173-180(1987).
"A Monoclonal Antibody-Based Enzyme Immunoassay for Fibrin Degradatiion Products in Plasma", Koppert et al., Thrombosis and Haemostasis, 59(2):310-315(1988).
"Automated Nephelometric Immunoassays With Novel Shell/Core Particles", Kapmeyer et al., Journal of Clinical Laboratory Analysis, 2:76-83(1988).
Henschen, A., et al., "Covalent Structure of Fibrinogen" Annals of the New York Academy of Science 408:28-43, 1983.
Rose, N. R., et al., eds. Manual of Clinical Laboratory Immunology, Washington, D.C.: American Society for Microbiology, 1986, pp. 24-42 and 99-108.
Sevier, E. D. et al. "Monoclonal Antibodies in Clinical Immunology", 27(11) :1797-1806, 1981.
P. Tijssen, Practice and Theory of Enzyme Immunoassays, In: Laboratory Techniques in Biochemistry and Molecular Biology vol. 15 New York: Elsevier, 1985, pp. 108-109.
J. P. Chen et al. "Radioimmunoassay of Fragment E-related neoantigen: Validation Studies and Clinical Applications" Journal of Haematology 57: 133-144, 1984.
S. A. Olexa et al. "Structure of Fragment E species from Human Cross-linked Fibrin" Biochemistry 21:6139-6145, 1981.
T. M. Price, et al. "Shadow-cast electron-microscopy of fibrinogen with antibody fragment bound to specific regions Proceedings of the National Academy of Science USA" 78(1) 200-204, 1981.

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