Antibodies which bind with proteins of human...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds virus or component thereof

Reexamination Certificate

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C424S148100, C424S130100

Reexamination Certificate

active

07122188

ABSTRACT:
This invention provides antibodies which bind with p12 and p18 proteins of a human immunodeficiency virus type 1 (HIV-1), antibodies which bind with immune complexes comprising p12 or p18 proteins of HIV-1, mixtures of antibodies which bind with p12, p15, p18, p25, p36, p42, and p80 proteins of HIV-1, mixtures of antibodies which bind with immune complexes comprising the HIV-1 proteins, immune complexes comprising p12 or p18 proteins of HIV-1, and methods for production of antibodies against p2 or p18 proteins of HIV-1.

REFERENCES:
patent: 4843011 (1989-06-01), Sarngadharan et al.
patent: 5156949 (1992-10-01), Luciw et al.
patent: 5217861 (1993-06-01), Montagnier et al.
Barre-Sinoussi: “Analysis and Immunological Properties of LAV Strucutal Proteins” Retroviruses Hum Pathol, Meeting Abstract Only.
Higgins, P., 1980 “Immunogenicity of agarose-immobilized immune complexes”, Experientia 36:889-890.
McDougal et al., 1985, “Immunoassay for the detection and quantitation of infectious human retrovirus, lymphadenopathy-associated virus (LAV)”, J. Immunol. Methods 76:171-183.
Barre-Sinoussi et al., 1985, “Analysis and immunological properties of lymphadenopathy associated virus (LAV) structural proteins”, Retroviruses Hum. Pathol. Int. Symp., meeting abstract.

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